ATG7 deficiency suppresses apoptosis and cell death induced by lysosomal photodamage

Photodynamic therapy (PDT) involves photosensitizing agents that, in the presence of oxygen and light, initiate formation of cytotoxic reactive oxygen species (ROS). PDT commonly induces both apoptosis and autophagy. Previous studies with murine hepatoma 1c1c7 cells indicated that loss of autophagy-...

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Bibliographic Details
Main Authors: Kessel, David H., Price, Michael, Reiners, Jr., John J.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Basic Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442880/
https://ncbi.nlm.nih.gov/pubmed/22889762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20792
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