Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K−Akt/p-HDAC6 Signaling Pathway

OBJECTIVE—: Cathepsin S (CatS) participates in atherogenesis through several putative mechanisms. The ability of cathepsins to modify histone tail is likely to contribute to stem cell development. Histone deacetylase 6 (HDAC6) is required in modulating the proliferation and migration of various type...

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Bibliografiset tiedot
Julkaisussa:Arterioscler Thromb Vasc Biol
Päätekijät: Wu, Hongxian, Cheng, Xian Wu, Hu, Lina, Takeshita, Kyosuke, Hu, Chen, Du, Qiuna, Li, Xiang, Zhu, Enbo, Huang, Zhe, Yisireyili, Maimaiti, Zhao, Guangxian, Piao, Limei, Inoue, Aiko, Jiang, Haiying, Lei, Yanna, Zhang, Xiaohong, Liu, Shaowen, Dai, Qiuyan, Kuzuya, Masafumi, Shi, Guo-Ping, Murohara, Toyoaki
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Lippincott Williams & Wilkins 2016
Aiheet:
Basic Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961274/
https://ncbi.nlm.nih.gov/pubmed/27365406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.307110
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