Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K−Akt/p-HDAC6 Signaling Pathway

OBJECTIVE—: Cathepsin S (CatS) participates in atherogenesis through several putative mechanisms. The ability of cathepsins to modify histone tail is likely to contribute to stem cell development. Histone deacetylase 6 (HDAC6) is required in modulating the proliferation and migration of various type...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Wu, Hongxian, Cheng, Xian Wu, Hu, Lina, Takeshita, Kyosuke, Hu, Chen, Du, Qiuna, Li, Xiang, Zhu, Enbo, Huang, Zhe, Yisireyili, Maimaiti, Zhao, Guangxian, Piao, Limei, Inoue, Aiko, Jiang, Haiying, Lei, Yanna, Zhang, Xiaohong, Liu, Shaowen, Dai, Qiuyan, Kuzuya, Masafumi, Shi, Guo-Ping, Murohara, Toyoaki
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
Assuntos:
Basic Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961274/
https://ncbi.nlm.nih.gov/pubmed/27365406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.307110
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