Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K−Akt/p-HDAC6 Signaling Pathway

OBJECTIVE—: Cathepsin S (CatS) participates in atherogenesis through several putative mechanisms. The ability of cathepsins to modify histone tail is likely to contribute to stem cell development. Histone deacetylase 6 (HDAC6) is required in modulating the proliferation and migration of various type...

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Dades bibliogràfiques
Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Wu, Hongxian, Cheng, Xian Wu, Hu, Lina, Takeshita, Kyosuke, Hu, Chen, Du, Qiuna, Li, Xiang, Zhu, Enbo, Huang, Zhe, Yisireyili, Maimaiti, Zhao, Guangxian, Piao, Limei, Inoue, Aiko, Jiang, Haiying, Lei, Yanna, Zhang, Xiaohong, Liu, Shaowen, Dai, Qiuyan, Kuzuya, Masafumi, Shi, Guo-Ping, Murohara, Toyoaki
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2016
Matèries:
Basic Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961274/
https://ncbi.nlm.nih.gov/pubmed/27365406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.307110
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