Resveratrol Inhibits Aortic Root Dilatation in the Fbn1(C1039G/+) Marfan Mouse Model

OBJECTIVE—: Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the fibrillin-1 gene. Patients with MFS are at risk of aortic aneurysm formation and dissection. Usually, blood pressure–lowering drugs are used to reduce aortic events; however, this is not sufficient for most...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Hibender, Stijntje, Franken, Romy, van Roomen, Cindy, ter Braake, Anique, van der Made, Ingeborg, Schermer, Edith E., Gunst, Quinn, van den Hoff, Maurice J., Lutgens, Esther, Pinto, Yigal M., Groenink, Maarten, Zwinderman, Aeilko H., Mulder, Barbara J.M., de Vries, Carlie J.M., de Waard, Vivian
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
Assuntos:
Basic Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961273/
https://ncbi.nlm.nih.gov/pubmed/27283746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307841
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