DNA binding triggers tetramerization of the glucocorticoid receptor in live cells

Transcription factors dynamically bind to chromatin and are essential for the regulation of genes. Although a large percentage of these proteins appear to self-associate to form dimers or higher order oligomers, the stoichiometry of DNA-bound transcription factors has been poorly characterized in vi...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Presman, Diego M., Ganguly, Sourav, Schiltz, R. Louis, Johnson, Thomas A., Karpova, Tatiana S., Hager, Gordon L.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2016
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961135/
https://ncbi.nlm.nih.gov/pubmed/27382178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606774113
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