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Harnessing the Endocannabinoid 2-Arachidonoylglycerol to Lower Intraocular Pressure in a Murine Model
PURPOSE: Cannabinoids, such as Δ(9)-THC, act through an endogenous signaling system in the vertebrate eye that reduces IOP via CB(1) receptors. Endogenous cannabinoid (eCB) ligand, 2-arachidonoyl glycerol (2-AG), likewise activates CB(1) and is metabolized by monoacylglycerol lipase (MAGL). We inves...
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| Publicado no: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4961057/ https://ncbi.nlm.nih.gov/pubmed/27333182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19356 |
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