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Harnessing the Endocannabinoid 2-Arachidonoylglycerol to Lower Intraocular Pressure in a Murine Model
PURPOSE: Cannabinoids, such as Δ(9)-THC, act through an endogenous signaling system in the vertebrate eye that reduces IOP via CB(1) receptors. Endogenous cannabinoid (eCB) ligand, 2-arachidonoyl glycerol (2-AG), likewise activates CB(1) and is metabolized by monoacylglycerol lipase (MAGL). We inves...
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| Publicat a: | Invest Ophthalmol Vis Sci |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Association for Research in Vision and Ophthalmology
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4961057/ https://ncbi.nlm.nih.gov/pubmed/27333182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19356 |
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