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Structures of multidrug and toxic compound extrusion transporters and their mechanistic implications

Multidrug resistance poses grand challenges to the effective treatment of infectious diseases and cancers. Integral membrane proteins from the multidrug and toxic compound extrusion (MATE) family contribute to multidrug resistance by exporting a wide variety of therapeutic drugs across cell membrane...

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Vydáno v:Channels (Austin)
Hlavní autor: Lu, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960993/
https://ncbi.nlm.nih.gov/pubmed/26488689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2015.1106654
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