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Structures of multidrug and toxic compound extrusion transporters and their mechanistic implications

Multidrug resistance poses grand challenges to the effective treatment of infectious diseases and cancers. Integral membrane proteins from the multidrug and toxic compound extrusion (MATE) family contribute to multidrug resistance by exporting a wide variety of therapeutic drugs across cell membrane...

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Détails bibliographiques
Publié dans:Channels (Austin)
Auteur principal: Lu, Min
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960993/
https://ncbi.nlm.nih.gov/pubmed/26488689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2015.1106654
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