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Structures of multidrug and toxic compound extrusion transporters and their mechanistic implications

Multidrug resistance poses grand challenges to the effective treatment of infectious diseases and cancers. Integral membrane proteins from the multidrug and toxic compound extrusion (MATE) family contribute to multidrug resistance by exporting a wide variety of therapeutic drugs across cell membrane...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Autor principal: Lu, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960993/
https://ncbi.nlm.nih.gov/pubmed/26488689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2015.1106654
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