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The Mouse Fetal Ovary Has Greater Sensitivity Than the Fetal Testis to Benzo[a]pyrene-Induced Germ Cell Death

The polycyclic aromatic hydrocarbon pollutant benzo[a]pyrene (BaP) is a known developmental gonadotoxicant. However, the mechanism of BaP-induced germ cell death is unclear. We investigated whether exposure to BaP induces apoptotic germ cell death in the mouse fetal ovary or testis. Mouse fetal gona...

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Vydáno v:Toxicol Sci
Hlavní autoři: Lim, Jinhwan, Kong, Weixi, Lu, Muzi, Luderer, Ulrike
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960906/
https://ncbi.nlm.nih.gov/pubmed/27208085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw083
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