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Hyperthermia induced HIF-1a expression of lung cancer through AKT and ERK signaling pathways

BACKGROUND: Hyperthermia is a promising treatment for human lung cancer, but recurrence of the primary lesion is common, as the residual tumor becomes adapted to heat treatment and growth is induced by hypoxia-triggered HIF-1a expression. Here, we explored the effects of hyperthermia on HIF-1a expre...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Wan, Jun, Wu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960890/
https://ncbi.nlm.nih.gov/pubmed/27456341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0399-7
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