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Hyperthermia induced HIF-1a expression of lung cancer through AKT and ERK signaling pathways

BACKGROUND: Hyperthermia is a promising treatment for human lung cancer, but recurrence of the primary lesion is common, as the residual tumor becomes adapted to heat treatment and growth is induced by hypoxia-triggered HIF-1a expression. Here, we explored the effects of hyperthermia on HIF-1a expre...

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Podrobná bibliografie
Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Wan, Jun, Wu, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960890/
https://ncbi.nlm.nih.gov/pubmed/27456341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0399-7
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