TCDD Promotes Lung Tumors via Attenuation of Apoptosis through Activation of the Akt and ERK1/2 Signaling Pathways

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a multiple-site, multiple-species carcinogen that induces cancer in multiple organs. The molecular mechanisms underlying TCDD-induced lung tumorigenesis remain unclear. In the present study, a two-stage lung tumorigenesis model was established by adminis...

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Detalhes bibliográficos
Main Authors: Chen, Rong-Jane, Siao, Shih-He, Hsu, Chung-Huei, Chang, Chu-Yung, Chang, Louis W., Wu, Chih-Hsiung, Lin, Pinpin, Wang, Ying-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057150/
https://ncbi.nlm.nih.gov/pubmed/24927102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099586
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