Topoisomerase IIβ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs

BACKGROUND: Glioblastoma stem cells (GSC) have been extensively recognized as a plausible cause of glioblastoma resistance to therapy and recurrence resulting in high glioblastoma mortality. Abnormalities in the DNA repair pathways might be responsible for the inability of the currently used chemoth...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Cell Int
Egile Nagusiak: Kenig, Saša, Faoro, Valentina, Bourkoula, Evgenia, Podergajs, Neža, Ius, Tamara, Vindigni, Marco, Skrap, Miran, Lah, Tamara, Cesselli, Daniela, Storici, Paola, Vindigni, Alessandro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Primary Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960855/
https://ncbi.nlm.nih.gov/pubmed/27462186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0339-9
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