The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation

BACKGROUND: RecQ helicases play an essential role in the maintenance of genome stability. In humans, loss of RecQ helicase function is linked with predisposition to cancer and/or premature ageing. Current data show that the specific depletion of the human RECQ1 helicase leads to mitotic catastrophe...

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Détails bibliographiques
Auteurs principaux: Mendoza-Maldonado, Ramiro, Faoro, Valentina, Bajpai, Sailesh, Berti, Matteo, Odreman, Federico, Vindigni, Marco, Ius, Tamara, Ghasemian, Abdollah, Bonin, Serena, Skrap, Miran, Stanta, Giorgio, Vindigni, Alessandro
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148559/
https://ncbi.nlm.nih.gov/pubmed/21752281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-83
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