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Topoisomerase IIβ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs

BACKGROUND: Glioblastoma stem cells (GSC) have been extensively recognized as a plausible cause of glioblastoma resistance to therapy and recurrence resulting in high glioblastoma mortality. Abnormalities in the DNA repair pathways might be responsible for the inability of the currently used chemoth...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Kenig, Saša, Faoro, Valentina, Bourkoula, Evgenia, Podergajs, Neža, Ius, Tamara, Vindigni, Marco, Skrap, Miran, Lah, Tamara, Cesselli, Daniela, Storici, Paola, Vindigni, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960855/
https://ncbi.nlm.nih.gov/pubmed/27462186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0339-9
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