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Topoisomerase IIβ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs
BACKGROUND: Glioblastoma stem cells (GSC) have been extensively recognized as a plausible cause of glioblastoma resistance to therapy and recurrence resulting in high glioblastoma mortality. Abnormalities in the DNA repair pathways might be responsible for the inability of the currently used chemoth...
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Publicado no: | Cancer Cell Int |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4960855/ https://ncbi.nlm.nih.gov/pubmed/27462186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0339-9 |
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