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Empagliflozin (an SGLT2 inhibitor), alone or in combination with linagliptin (a DPP-4 inhibitor), prevents steatohepatitis in a novel mouse model of non-alcoholic steatohepatitis and diabetes

BACKGROUND: Sodium-glucose co-transporter-2 (SGLT2) inhibitors are new oral antidiabetic drugs that reduce hyperglycemia by promoting urinary glucose excretion. Glycosuria produced by SGLT2 inhibitors is associated with weight loss, mainly due to reduced fat volume. We investigated the effects of em...

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Detalles Bibliográficos
Publicado en:Diabetol Metab Syndr
Main Authors: Jojima, Teruo, Tomotsune, Takanori, Iijima, Toshie, Akimoto, Kazumi, Suzuki, Kunihiro, Aso, Yoshimasa
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960737/
https://ncbi.nlm.nih.gov/pubmed/27462372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-016-0169-x
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