SGLT2 Inhibitor Empagliflozin and DPP4 Inhibitor Linagliptin Reactivate Glomerular Autophagy in db/db Mice, a Model of Type 2 Diabetes

Recent data have indicated the emerging role of glomerular autophagy in diabetic kidney disease. We aimed to assess the effect of the SGLT2 inhibitor empagliflozin, the DPP4 inhibitor linagliptin, and their combination, on glomerular autophagy in a model of type 2 diabetes. Eight-week-old male db/db...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Korbut, Anton I., Taskaeva, Iuliia S., Bgatova, Nataliya P., Muraleva, Natalia A., Orlov, Nikolai B., Dashkin, Maksim V., Khotskina, Anna S., Zavyalov, Evgenii L., Konenkov, Vladimir I., Klein, Thomas, Klimontov, Vadim V.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215949/
https://ncbi.nlm.nih.gov/pubmed/32340263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082987
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