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ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments

BACKGROUND: Cachexia affects the majority of patients with advanced cancer and is associated with reduced treatment tolerance, response to therapy, quality of life, and life expectancy. Cachectic patients with advanced cancer often receive anti-cancer therapies against their specific cancer type as...

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Pubblicato in:Skelet Muscle
Autori principali: Hatakeyama, Shinji, Summermatter, Serge, Jourdain, Marie, Melly, Stefan, Minetti, Giulia C., Lach-Trifilieff, Estelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960708/
https://ncbi.nlm.nih.gov/pubmed/27462398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-016-0098-2
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