Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia

BACKGROUND: Cachexia, a multifactorial syndrome affecting more than 50% of patients with advanced cancer and responsible for ~20% of cancer‐associated deaths, is still a poorly understood process without a standard cure available. Skeletal muscle atrophy caused by systemic inflammation is a major cl...

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Dettagli Bibliografici
Pubblicato in:J Cachexia Sarcopenia Muscle
Autori principali: Chiappalupi, Sara, Sorci, Guglielmo, Vukasinovic, Aleksandra, Salvadori, Laura, Sagheddu, Roberta, Coletti, Dario, Renga, Giorgia, Romani, Luigina, Donato, Rosario, Riuzzi, Francesca
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432590/
https://ncbi.nlm.nih.gov/pubmed/32159297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12561
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