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ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments

BACKGROUND: Cachexia affects the majority of patients with advanced cancer and is associated with reduced treatment tolerance, response to therapy, quality of life, and life expectancy. Cachectic patients with advanced cancer often receive anti-cancer therapies against their specific cancer type as...

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Publicado en:Skelet Muscle
Main Authors: Hatakeyama, Shinji, Summermatter, Serge, Jourdain, Marie, Melly, Stefan, Minetti, Giulia C., Lach-Trifilieff, Estelle
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960708/
https://ncbi.nlm.nih.gov/pubmed/27462398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-016-0098-2
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