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ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments

BACKGROUND: Cachexia affects the majority of patients with advanced cancer and is associated with reduced treatment tolerance, response to therapy, quality of life, and life expectancy. Cachectic patients with advanced cancer often receive anti-cancer therapies against their specific cancer type as...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Skelet Muscle
Prif Awduron: Hatakeyama, Shinji, Summermatter, Serge, Jourdain, Marie, Melly, Stefan, Minetti, Giulia C., Lach-Trifilieff, Estelle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960708/
https://ncbi.nlm.nih.gov/pubmed/27462398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-016-0098-2
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