Toll-like Receptor 7 Is Reduced in Severe Asthma and Linked to an Altered MicroRNA Profile

Rationale: Asthma is one of the most common chronic diseases worldwide, and individuals with severe asthma experience recurrent exacerbations. Exacerbations are predominantly viral associated and have been linked to defective airway IFN responses. Ascertaining the molecular mechanisms underlying thi...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Rupani, Hitasha, Martinez-Nunez, Rocio T., Dennison, Patrick, Lau, Laurie C. K., Jayasekera, Nivenka, Havelock, Tom, Francisco-Garcia, Ana S., Grainge, Christopher, Howarth, Peter H., Sanchez-Elsner, Tilman
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960627/
https://ncbi.nlm.nih.gov/pubmed/26815632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201502-0280OC
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