Toll-like Receptor 7 Is Reduced in Severe Asthma and Linked to an Altered MicroRNA Profile

Rationale: Asthma is one of the most common chronic diseases worldwide, and individuals with severe asthma experience recurrent exacerbations. Exacerbations are predominantly viral associated and have been linked to defective airway IFN responses. Ascertaining the molecular mechanisms underlying thi...

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Pubblicato in:Am J Respir Crit Care Med
Autori principali: Rupani, Hitasha, Martinez-Nunez, Rocio T., Dennison, Patrick, Lau, Laurie C. K., Jayasekera, Nivenka, Havelock, Tom, Francisco-Garcia, Ana S., Grainge, Christopher, Howarth, Peter H., Sanchez-Elsner, Tilman
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960627/
https://ncbi.nlm.nih.gov/pubmed/26815632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201502-0280OC
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