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MicroRNA-155 Targets SMAD2 and Modulates the Response of Macrophages to Transforming Growth Factor-β

Transforming growth factor-beta (TGF-β) is a pleiotropic cytokine with important effects on processes such as fibrosis, angiogenesis, and immunosupression. Using bioinformatics, we identified SMAD2, one of the mediators of TGF-β signaling, as a predicted target for a microRNA, microRNA-155 (miR-155)...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Louafi, Fethi, Martinez-Nunez, Rocio T., Sanchez-Elsner, Tilman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
RNA
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009858/
https://ncbi.nlm.nih.gov/pubmed/21036908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146852
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