Broccoli sprout extract prevents diabetic cardiomyopathy via Nrf2 activation in db/db T2DM mice

To develop a clinic-relevant protocol for systemic up-regulation of NFE2-related factor 2 (Nrf2) to prevent diabetic cardiomyopathy (DCM), male db/db and age-matched wild-type (WT) mice were given sulforaphane (SFN, an Nrf2 activator) and its natural source, broccoli sprout extract (BSE) by gavage e...

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Vydáno v:Sci Rep
Hlavní autoři: Xu, Zheng, Wang, Shudong, Ji, Honglei, Zhang, Zhiguo, Chen, Jing, Tan, Yi, Wintergerst, Kupper, Zheng, Yang, Sun, Jian, Cai, Lu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960533/
https://ncbi.nlm.nih.gov/pubmed/27457280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30252
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