Common alleles contribute to schizophrenia in CNV carriers

The genetic architecture of schizophrenia is complex, involving risk alleles ranging from common alleles of weak effect to rare alleles of large effect, the best exemplar of the latter being large copy number variants (CNVs). It is currently unknown whether pathophysiology in those with defined rare...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Psychiatry
Main Authors: Tansey, K E, Rees, E, Linden, D E, Ripke, S, Chambert, K D, Moran, J L, McCarroll, S A, Holmans, P, Kirov, G, Walters, J, Owen, M J, O'Donovan, M C
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960448/
https://ncbi.nlm.nih.gov/pubmed/26390827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.143
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