Common alleles contribute to schizophrenia in CNV carriers

The genetic architecture of schizophrenia is complex, involving risk alleles ranging from common alleles of weak effect to rare alleles of large effect, the best exemplar of the latter being large copy number variants (CNVs). It is currently unknown whether pathophysiology in those with defined rare...

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Vydáno v:Mol Psychiatry
Hlavní autoři: Tansey, K E, Rees, E, Linden, D E, Ripke, S, Chambert, K D, Moran, J L, McCarroll, S A, Holmans, P, Kirov, G, Walters, J, Owen, M J, O'Donovan, M C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960448/
https://ncbi.nlm.nih.gov/pubmed/26390827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.143
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