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Common alleles contribute to schizophrenia in CNV carriers

The genetic architecture of schizophrenia is complex, involving risk alleles ranging from common alleles of weak effect to rare alleles of large effect, the best exemplar of the latter being large copy number variants (CNVs). It is currently unknown whether pathophysiology in those with defined rare...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Tansey, K E, Rees, E, Linden, D E, Ripke, S, Chambert, K D, Moran, J L, McCarroll, S A, Holmans, P, Kirov, G, Walters, J, Owen, M J, O'Donovan, M C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960448/
https://ncbi.nlm.nih.gov/pubmed/26390827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.143
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