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Pancreatic Islet Hepatocyte Growth Factor and Vascular Endothelial Growth Factor A Signaling in Growth Restricted Fetuses

Placental insufficiency leads to intrauterine growth restriction (IUGR) and a lifelong risk of developing type 2 diabetes. Impaired islet development in the growth restricted fetus, including decreased β-cell replication, mass, and insulin secretion, is strongly implicated in the pathogenesis of lat...

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Detalhes bibliográficos
Publicado no:Mol Cell Endocrinol
Main Authors: Rozance, Paul J, Hay, William W
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959995/
https://ncbi.nlm.nih.gov/pubmed/26820125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2016.01.025
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