Placental Insufficiency Decreases Pancreatic Vascularity and Disrupts Hepatocyte Growth Factor Signaling in the Pancreatic Islet Endothelial Cell in Fetal Sheep

Hepatocyte growth factor (HGF) and vascular endothelial growth factor A (VEGFA) are paracrine hormones that mediate communication between pancreatic islet endothelial cells (ECs) and β-cells. Our objective was to determine the impact of intrauterine growth restriction (IUGR) on pancreatic vascularit...

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Bibliographische Detailangaben
Veröffentlicht in:Diabetes
Hauptverfasser: Rozance, Paul J., Anderson, Miranda, Martinez, Marina, Fahy, Anna, Macko, Antoni R., Kailey, Jenai, Seedorf, Gregory J., Abman, Steven H., Hay, William W., Limesand, Sean W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2015
Schlagworte:
Islet Studies
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303968/
https://ncbi.nlm.nih.gov/pubmed/25249573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0462
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