Direct modulation of TRPM4 and TRPM3 channels by the phospholipase C inhibitor U73122

BACKGROUND AND PURPOSE: Signalling through phospholipase C (PLC) controls many cellular processes. Much information on the relevance of this important pathway has been derived from pharmacological inhibition of the enzymatic activity of PLC. We found that the most frequently employed PLC inhibitor,...

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Bibliografische gegevens
Gepubliceerd in:Br J Pharmacol
Hoofdauteurs: Leitner, Michael G, Michel, Niklas, Behrendt, Marc, Dierich, Marlen, Dembla, Sandeep, Wilke, Bettina U, Konrad, Maik, Lindner, Moritz, Oberwinkler, Johannes, Oliver, Dominik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959952/
https://ncbi.nlm.nih.gov/pubmed/27328745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13538
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