Structural requirements of steroidal agonists of transient receptor potential melastatin 3 (TRPM3) cation channels

BACKGROUND AND PURPOSE: Transient receptor potential melastatin 3 (TRPM3) proteins form non-selective but calcium-permeable membrane channels, rapidly activated by extracellular application of the steroid pregnenolone sulphate and the dihydropyridine nifedipine. Our aim was to characterize the stero...

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Detalhes bibliográficos
Main Authors: Drews, A, Mohr, F, Rizun, O, Wagner, T F J, Dembla, S, Rudolph, S, Lambert, S, Konrad, M, Philipp, S E, Behrendt, M, Marchais-Oberwinkler, S, Covey, D F, Oberwinkler, J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925040/
https://ncbi.nlm.nih.gov/pubmed/24251620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12521
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