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Direct modulation of TRPM4 and TRPM3 channels by the phospholipase C inhibitor U73122

BACKGROUND AND PURPOSE: Signalling through phospholipase C (PLC) controls many cellular processes. Much information on the relevance of this important pathway has been derived from pharmacological inhibition of the enzymatic activity of PLC. We found that the most frequently employed PLC inhibitor,...

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書目詳細資料
發表在:Br J Pharmacol
Main Authors: Leitner, Michael G, Michel, Niklas, Behrendt, Marc, Dierich, Marlen, Dembla, Sandeep, Wilke, Bettina U, Konrad, Maik, Lindner, Moritz, Oberwinkler, Johannes, Oliver, Dominik
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959952/
https://ncbi.nlm.nih.gov/pubmed/27328745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13538
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