Direct modulation of TRPM4 and TRPM3 channels by the phospholipase C inhibitor U73122

BACKGROUND AND PURPOSE: Signalling through phospholipase C (PLC) controls many cellular processes. Much information on the relevance of this important pathway has been derived from pharmacological inhibition of the enzymatic activity of PLC. We found that the most frequently employed PLC inhibitor,...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Leitner, Michael G, Michel, Niklas, Behrendt, Marc, Dierich, Marlen, Dembla, Sandeep, Wilke, Bettina U, Konrad, Maik, Lindner, Moritz, Oberwinkler, Johannes, Oliver, Dominik
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959952/
https://ncbi.nlm.nih.gov/pubmed/27328745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13538
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