FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

BACKGROUND: Genomewide association studies can be used to identify disease-relevant genomic regions, but interpretation of the data is challenging. The FTO region harbors the strongest genetic association with obesity, yet the mechanistic basis of this association remains elusive. METHODS: We examin...

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Publicado no:N Engl J Med
Main Authors: Claussnitzer, Melina, Dankel, Simon N., Kim, Kyoung-Han, Quon, Gerald, Meuleman, Wouter, Haugen, Christine, Glunk, Viktoria, Sousa, Isabel S., Beaudry, Jacqueline L., Puviindran, Vijitha, Abdennur, Nezar A., Liu, Jannel, Svensson, Per-Arne, Hsu, Yi-Hsiang, Drucker, Daniel J., Mellgren, Gunnar, Hui, Chi-Chung, Hauner, Hans, Kellis, Manolis
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959911/
https://ncbi.nlm.nih.gov/pubmed/26287746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1502214
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