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ORMDL proteins regulate ceramide levels during sterile inflammation

The bioactive sphingolipid metabolite, ceramide, regulates physiological processes important for inflammation and elevated levels of ceramide have been implicated in IL-1-mediated events. Although much has been learned about ceramide generation by activation of sphingomyelinases in response to IL-1,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Lipid Res
Hauptverfasser: Cai, Lin, Oyeniran, Clement, Biswas, Debolina D., Allegood, Jeremy, Milstien, Sheldon, Kordula, Tomasz, Maceyka, Michael, Spiegel, Sarah
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959857/
https://ncbi.nlm.nih.gov/pubmed/27313060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M065920
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