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ORMDL3 and allergic asthma: From physiology to pathology

There is a strong genetic component to asthma, and numerous genome-wide association studies have identified ORM1 (yeast)–like protein 3 (ORMDL3) as a gene associated with asthma susceptibility. However, how ORMDL3 contributes to asthma pathogenesis and its physiologic functions is not well understoo...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: James, Briana, Milstien, Sheldon, Spiegel, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910079/
https://ncbi.nlm.nih.gov/pubmed/31376405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.07.023
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