Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice

Sirtuin type 1 (Sirt1) and protein kinase B (Akt2) are associated with development of obesity and inflammation, but the molecular mechanisms of Sirt1 and Akt2 interaction on adipose inflammation remain unclear. To explore these mechanisms, a mouse model was used. Mice were fed with a high-fat diet (...

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Detaylı Bibliyografya
Yayımlandı:J Lipid Res
Asıl Yazarlar: Liu, Zhenjiang, Gan, Lu, Liu, Guannv, Chen, Yizhe, Wu, Tianjiao, Feng, Fei, Sun, Chao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2016
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959854/
https://ncbi.nlm.nih.gov/pubmed/27317762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M063537
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