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Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice
Sirtuin type 1 (Sirt1) and protein kinase B (Akt2) are associated with development of obesity and inflammation, but the molecular mechanisms of Sirt1 and Akt2 interaction on adipose inflammation remain unclear. To explore these mechanisms, a mouse model was used. Mice were fed with a high-fat diet (...
Enregistré dans:
| Publié dans: | J Lipid Res |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Biochemistry and Molecular Biology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959854/ https://ncbi.nlm.nih.gov/pubmed/27317762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M063537 |
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