Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue

Sirtuin 1 (Sirt1) promotes adaptive thermogenesis by controlling the acetylation status of enzymes and transcriptional factors in interscapular brown adipose tissue (iBAT). However, the effects of Sirt1 on endoplasmic reticulum (ER) stress and apoptosis of iBAT remain elusive. In this study, the mRN...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Zhenjiang, Gu, Huihui, Gan, Lu, Xu, Yatao, Feng, Fei, Saeed, Muhammad, Sun, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354730/
https://ncbi.nlm.nih.gov/pubmed/28030827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14035
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