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Involvement of the Eukaryote-Like Kinase-Phosphatase System and a Protein That Interacts with Penicillin-Binding Protein 5 in Emergence of Cephalosporin Resistance in Cephalosporin-Sensitive Class A Penicillin-Binding Protein Mutants in Enterococcus faecium
The intrinsic resistance of Enterococcus faecium to ceftriaxone and cefepime (here referred to as “cephalosporins”) is reliant on the presence of class A penicillin-binding proteins (Pbps) PbpF and PonA. Mutants lacking these Pbps exhibit cephalosporin susceptibility that is reversible by exposure t...
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Pubblicato in: | mBio |
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Autori principali: | , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society for Microbiology
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959515/ https://ncbi.nlm.nih.gov/pubmed/27048803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02188-15 |
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