Extracranial injections of botulinum neurotoxin type A inhibit intracranial meningeal nociceptors’ responses to stimulation of TRPV1 and TRPA1 channels: Are we getting closer to solving this puzzle?

BACKGROUND: Administration of onabotulinumtoxinA (BoNT-A) to peripheral tissues outside the calvaria reduces the number of days chronic migraine patients experience headache. Because the headache phase of a migraine attack, especially those preceded by aura, is thought to involve activation of menin...

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Detalhes bibliográficos
Publicado no:Cephalalgia
Main Authors: Zhang, XiChun, Strassman, Andrew M, Novack, Victor, Brin, Mitchell F, Burstein, Rami
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959034/
https://ncbi.nlm.nih.gov/pubmed/26984967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0333102416636843
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