Exploring the effects of extracranial injections of botulinum toxin type A on prolonged intracranial meningeal nociceptors responses to cortical spreading depression in female rats

BACKGROUND: Botulinum neurotoxin type A, an FDA-approved prophylactic drug for chronic migraine, is thought to achieve its therapeutic effect through blocking activation of unmyelinated meningeal nociceptors and their downstream communications with myelinated nociceptors and potentially the vasculat...

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Vydáno v:Cephalalgia
Hlavní autoři: Melo-Carrillo, Agustin, Strassman, Andrew M, Schain, Aaron J, Noseda, Rodrigo, Ashina, Sait, Adams, Aubrey, Brin, Mitchell F, Burstein, Rami
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779016/
https://ncbi.nlm.nih.gov/pubmed/31475573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0333102419873675
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