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The unfolded protein response: mechanisms and therapy of neurodegeneration

Activation of the unfolded protein response is emerging as a common theme in protein-misfolding neurodegenerative diseases, with relevant markers observed in patient tissue and mouse models. Genetic and pharmacological manipulation of the pathway in several mouse models has shown that this is not a...

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Bibliografische gegevens
Gepubliceerd in:Brain
Hoofdauteurs: Smith, Heather L., Mallucci, Giovanna R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958893/
https://ncbi.nlm.nih.gov/pubmed/27190028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aww101
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