Development and Evaluation of a Gentamicin Pharmacokinetic Model That Facilitates Opportunistic Gentamicin Therapeutic Drug Monitoring in Neonates and Infants

Trough gentamicin therapeutic drug monitoring (TDM) is time-consuming, disruptive to neonatal clinical care, and a patient safety issue. Bayesian models could allow TDM to be performed opportunistically at the time of routine blood tests. This study aimed to develop and prospectively evaluate a new...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Germovsek, Eva, Kent, Alison, Metsvaht, Tuuli, Lutsar, Irja, Klein, Nigel, Turner, Mark A., Sharland, Mike, Nielsen, Elisabet I., Heath, Paul T., Standing, Joseph F.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Clinical Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958175/
https://ncbi.nlm.nih.gov/pubmed/27270281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00577-16
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