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Plasma and CSF pharmacokinetics of meropenem in neonates and young infants: results from the NeoMero studies

BACKGROUND: Sepsis and bacterial meningitis are major causes of mortality and morbidity in neonates and infants. Meropenem, a broad-spectrum antibiotic, is not licensed for use in neonates and infants below 3 months of age and sufficient information on its plasma and CSF disposition and dosing in ne...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Germovsek, Eva, Lutsar, Irja, Kipper, Karin, Karlsson, Mats O, Planche, Tim, Chazallon, Corine, Meyer, Laurence, Trafojer, Ursula M T, Metsvaht, Tuuli, Fournier, Isabelle, Sharland, Mike, Heath, Paul, Standing, Joseph F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005047/
https://ncbi.nlm.nih.gov/pubmed/29684147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky128
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