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Modulation of Vincristine and Doxorubicin Binding and Release from Silk Films

Sustained release drug delivery systems remain a major clinical need for small molecule therapeutics in oncology. Here, mechanisms of small molecule interactions with silk protein films were studied with cationic oncology drugs, vincristine and doxorubicin, with a focus on hydrophobicity (non-ionic...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Coburn, Jeannine M., Na, Elim, Kaplan, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957972/
https://ncbi.nlm.nih.gov/pubmed/26500149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.10.035
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