Surgery combined with controlled-release doxorubicin silk films as a treatment strategy in an orthotopic neuroblastoma mouse model

BACKGROUND: Neuroblastoma tumour resection goal is maximal tumour removal. We hypothesise that combining surgery with sustained, local doxorubicin application can control tumour growth. METHODS: We injected human neuroblastoma cells into immunocompromised mouse adrenal gland. When KELLY cell-induced...

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Autori principali: Chiu, B, Coburn, J, Pilichowska, M, Holcroft, C, Seib, F P, Charest, A, Kaplan, D L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
Soggetti:
Translational Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134491/
https://ncbi.nlm.nih.gov/pubmed/24921912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.324
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