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Differentiating mTOR Inhibitors in Renal Cell Carcinoma

PI3K/Akt/mTOR signalling is dysregulated in many cancers, including renal cell carcinoma (RCC), and activation of this pathway has been suggested to correlate with aggressive behavior and poor prognosis in RCC tumors. mTOR inhibition plays a principal role in the targeted treatment of many cancer ty...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Treat Rev
Main Authors: Pal, Sumanta K., Quinn, David I.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957946/
https://ncbi.nlm.nih.gov/pubmed/23433636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2012.12.015
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